Intelligent design for
gene therapies and drug delivery

We apply cutting-edge machine learning to accelerate the discovery and optimization of innovative drug delivery systems — uniting computational modeling, chemical design, and rapid lab validation.

The computational edge in drug delivery.

Kosha is building an integrated platform for lipid nanoparticles powered by AI-driven computational design. We explore and iterate on molecular structures that improve how drugs are transported in the body.

AI is the core of our platform. Generative models design novel lipid structures from scratch, exploring regions of chemical space that traditional medicinal chemistry would never reach.

Predictive models then evaluate each candidate against properties like delivery efficiency, tissue tropism, and tolerability — narrowing millions of possibilities down to the few worth making.

The result is a design cycle measured in days, where every batch synthesized teaches the next generation of models.

Three pillars. One integrated loop.

01
Machine Learning

Cutting-edge ML models that predict and optimize molecular structures for enhanced drug transport — reducing experimental cycles from months to days.

02
Chemical Design

Computational exploration of vast chemical spaces to identify novel delivery candidates with precision, guided by multi-objective optimization algorithms.

03
Wet Lab Validation

State-of-the-art laboratory infrastructure for rapid synthesis and testing — closing the loop between in silico predictions and real-world experimental data.

Our discovery process.

Data & Models

ML-driven property prediction

Chemical Space

Vast candidate exploration

Synthesis

Rapid lab preparation

Testing

In vitro & in vivo assays

Iteration

Model refinement loop

Help us shape what's next.

Whether you're a scientist, engineer, investor, or collaborator — we'd love to hear from you.

StageEarly-stage · Building from the ground up